Kaija-Leena Kolho Selected Research

Pediatric ulcerative colitis

10/2020	Antibiotic Cocktail for Pediatric Acute Severe Colitis and the Microbiome: The PRASCO Randomized Controlled Trial.
8/2017	Mesalamine Enemas for Induction of Remission in Oral Mesalamine-refractory Pediatric Ulcerative Colitis: A Prospective Cohort Study.
11/2014	Combination of oral antibiotics may be effective in severe pediatric ulcerative colitis: a preliminary report.
1/2013	Fecal calprotectin and clinical disease activity in pediatric ulcerative colitis.
8/2012	Matrix metalloproteinases in the restorative proctocolectomy pouch of pediatric ulcerative colitis.
4/2012	Association of repeated exposure to antibiotics with the development of pediatric Crohn's disease--a nationwide, register-based finnish case-control study.
3/2010	Glucocorticoid bioactivity does not predict response to steroid therapy in severe pediatric ulcerative colitis.

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Kaija-Leena Kolho Research Topics

Disease

56	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 12/2023 - 06/2006
37	Crohn Disease (Crohn's Disease) 05/2024 - 01/2008
33	Inflammation (Inflammations) 10/2023 - 12/2005
25	Ulcerative Colitis 11/2022 - 05/2009
10	Colitis 07/2023 - 06/2006
7	Hypersensitivity (Allergy) 01/2022 - 04/2006
7	Pediatric ulcerative colitis 10/2020 - 03/2010
5	Infections 12/2023 - 01/2002
5	Pathologic Constriction (Stenosis) 01/2022 - 01/2019
4	Autoimmune Diseases (Autoimmune Disease) 05/2023 - 07/2021
4	Juvenile Arthritis (Juvenile Idiopathic Arthritis) 01/2023 - 04/2014
4	Neoplasms (Cancer) 11/2022 - 08/2011
4	Sclerosing Cholangitis 10/2021 - 11/2018
3	Cholangiocarcinoma 09/2023 - 01/2017
3	Pediatric Crohn's disease 01/2023 - 01/2012
3	Necrosis 10/2020 - 12/2010
3	Pouchitis 01/2020 - 03/2010
3	Fistula 03/2019 - 06/2007
3	Milk Hypersensitivity (Milk Allergy) 01/2018 - 04/2006
3	Parotitis (Parotiditis) 01/2016 - 11/2005
2	Fibrosis (Cirrhosis) 05/2024 - 05/2018
2	Disease Progression 08/2022 - 01/2019
2	Abscess 03/2019 - 06/2007
2	Intrahepatic Cholestasis 05/2018 - 07/2010
2	progressive familial intrahepatic 1 Cholestasis 05/2018 - 07/2010
2	Abdominal Pain (Pain, Abdominal) 01/2017 - 11/2015
2	Skin Manifestations 01/2016 - 08/2014
1	Urinary Tract Infections (Urinary Tract Infection) 12/2023
1	Weight Gain 01/2023
1	Adenocarcinoma 11/2022
1	Adenoma (Adenomas) 11/2022
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 07/2021
1	Premature Birth (Birth, Premature) 07/2021
1	Autoimmune Thyroiditis (Lymphomatous Thyroiditis) 07/2021
1	Failure to Thrive 01/2021
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2021
1	Nephritis 01/2021
1	Purpura 01/2021
1	Hypoalbuminemia 01/2021
1	Autoimmune Hepatitis 01/2020

Drug/Important Bio-Agent (IBA)

37	Leukocyte L1 Antigen Complex (Calgranulin)IBA 01/2023 - 06/2006
15	Biomarkers (Surrogate Marker)IBA 05/2023 - 01/2008
14	Infliximab (Remicade)FDA Link 01/2023 - 12/2011
13	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2023 - 10/2008
13	GlucocorticoidsIBA 01/2019 - 06/2006
11	Anti-Bacterial Agents (Antibiotics)IBA 12/2023 - 06/2007
8	Adrenal Cortex Hormones (Corticosteroids)IBA 05/2024 - 10/2009
7	Matrix Metalloproteinases (MMPs)IBA 01/2016 - 12/2005
5	gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA 01/2021 - 01/2017
5	Proteins (Proteins, Gene)FDA Link 05/2018 - 01/2008
5	Immunoglobulin E (IgE)IBA 01/2018 - 02/2005
5	AntibodiesIBA 01/2017 - 01/2002
4	SteroidsIBA 09/2023 - 03/2010
4	EnzymesIBA 01/2019 - 04/2006
4	LactoferrinIBA 10/2016 - 01/2008
3	vedolizumabIBA 10/2023 - 10/2017
3	Immunologic Factors (Immunomodulators)IBA 01/2022 - 01/2020
3	Adalimumab (Humira)FDA Link 01/2022 - 11/2012
3	BilirubinIBA 01/2021 - 01/2017
3	Prednisolone (Predate)FDA LinkGeneric 03/2019 - 10/2008
2	Ustekinumab (CNTO 1275)FDA Link 05/2024 - 12/2022
2	RNA (Ribonucleic Acid)IBA 01/2022 - 02/2012
2	Doxycycline (Periostat)FDA LinkGeneric 10/2020 - 11/2014
2	Ciprofloxacin (Cipro)FDA LinkGeneric 10/2020 - 11/2014
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2019 - 01/2017
2	Mesalamine (Mesalazine)FDA LinkGeneric 08/2017 - 05/2017
2	Folic Acid (Vitamin M)FDA LinkGeneric 03/2017 - 01/2007
2	Interleukin-17 (Interleukin 17)IBA 09/2013 - 01/2012
2	Messenger RNA (mRNA)IBA 09/2013 - 01/2012
2	InterleukinsIBA 09/2013 - 12/2010
2	C-Reactive ProteinIBA 02/2013 - 06/2010
2	Azathioprine (Imuran)FDA LinkGeneric 01/2012 - 10/2009
2	InterferonsIBA 01/2012 - 12/2010
2	Metalloproteases (Metalloproteinases)IBA 11/2010 - 10/2009
2	Tissue Inhibitor of Metalloproteinase-1IBA 11/2010 - 10/2009
2	Immunoglobulin G (IgG)IBA 10/2009 - 01/2002
2	Milk Proteins (Milk Protein)IBA 10/2009 - 01/2008
2	LactaseIBA 01/2009 - 04/2006
1	Prostaglandins AIBA 05/2024
1	Penicillins (Penicillin)FDA Link 01/2023
1	2-mercaptopurineIBA 01/2023
1	Proton Pump InhibitorsIBA 01/2023
1	Phenobarbital (Luminal)FDA Link 08/2022
1	ChloridesIBA 10/2021
1	Glycoproteins (Glycoprotein)IBA 02/2021
1	HLA-DRB1 Chains (HLA DRB1)IBA 01/2021
1	AlbuminsIBA 01/2021
1	HLA-DQ Antigens (HLA-DQ)IBA 01/2021
1	Metronidazole (Metric)FDA LinkGeneric 10/2020
1	Amoxicillin (Wymox)FDA LinkGeneric 10/2020
1	Vancomycin FDA LinkGeneric 10/2020
1	Transaminases (Aminotransferases)IBA 01/2020

Therapy/Procedure

38	Therapeutics 05/2024 - 06/2006
8	Liver Transplantation 05/2024 - 01/2017
7	Restorative Proctocolectomy 03/2024 - 05/2009
3	Enteral Nutrition (Feeding, Tube) 05/2024 - 01/2022
3	Colectomy 10/2021 - 03/2019
2	Cesarean Section (Caesarean Section) 12/2023 - 01/2022
2	Ileostomy 10/2021 - 03/2019
1	Off-Label Use 10/2023